SCHEMBL6189119

SCHEMBL6189119

N=c1sc2cc(Cl)ccc2n1CC1CCN(CC(=O)c2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
ACHE P22303 3/20 0.40
CCR2 P41597 1/20 0.40
BCHE P06276 2/20 0.39
HTR2A P28223 2/20 0.38
HTR1A P08908 1/20 0.38
TMEM97 Q5BJF2 1/20 0.38
HTR2C P28335 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6192891 0.90 CXCR3 (0.43) ALDH1A1KCNH2
SCHEMBL8124528 0.90 HTR7 (0.42) ALDH1A1ACHECCR2HTR2AHTR1A
Hydrochloric Acid SCHEMBL6187266 0.90 DRD2 (0.44) ALDH1A1HTR2AHTR1ATMEM97HTR2C
SCHEMBL6192972 0.88 MEN1 (0.48) ALDH1A1
SCHEMBL6188892 0.88 KMT2A (0.38) CCR2HTR2AHTR1ATMEM97KCNH2
SCHEMBL6191286 0.88 CCR2 (0.38) ALDH1A1ACHECCR2HTR2AHTR1A
SCHEMBL6192255 0.88 MEN1 (0.48) ALDH1A1
SCHEMBL6189192 0.86 CNR1 (0.40) ALDH1A1ACHEHTR2AHTR2C
SCHEMBL6190514 0.82 MAPT (0.39) CCR2
Hydrochloric Acid SCHEMBL6187924 0.81 HTR2A (0.47) ALDH1A1HTR2AHTR1ATMEM97HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043319-B1 NOVEL ALKYLAMINO DERIVATIVES MITSUBISHI CHEM CORP (JP) 2005-03-16 EP disclosed
EP-1043319-A1 NOVEL ALKYLAMINO DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 2000-10-11 EP disclosed