Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188876 | 0.87 | HTR6 (0.58) | HTR6 | |
| SCHEMBL6236033 | 0.75 | HTR6 (0.52) | HTR6 | |
| SCHEMBL4659557 | 0.74 | HTR6 (0.62) | HTR6 | |
| SCHEMBL8090756 | 0.73 | HTR6 (0.63) | HTR6 | |
| SCHEMBL31587937 | 0.72 | MEN1 (0.59) | HTR6 | |
| SCHEMBL4416491 | 0.71 | HTR6 (0.80) | HTR6 | |
| SCHEMBL13979786 | 0.70 | HTR6 (0.65) | HTR6 | |
| SCHEMBL4550063 | 0.70 | HTR6 (0.49) | HTR6 | |
| SCHEMBL31588485 | 0.70 | HTR6 (0.53) | HTR6 | |
| SCHEMBL4659386 | 0.69 | HTR6 (0.60) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994862-B1 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 2005-06-01 | — | — | EP | claimed |