Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766243 | 0.87 | KDM4E (0.55) | L3MBTL1PTPN1PTGS2MAPK1KDM4E | |
| SCHEMBL7037844 | 0.86 | PTGS2 (0.46) | PTPN1PTGS2MAPK1KDM4EHSD17B10 | |
| SCHEMBL674008 | 0.84 | ALDH1A1 (0.52) | L3MBTL1GLAMAPK1KDM4EHSD17B10 | |
| SCHEMBL9825698 | 0.84 | ALDH1A1 (0.52) | L3MBTL1GLAMAPK1KDM4EHSD17B10 | |
| SCHEMBL4923575 | 0.83 | L3MBTL1 (0.61) | L3MBTL1GLAPTGS2KDM4EHSD17B10 | |
| SCHEMBL6198803 | 0.80 | GABRA1 (0.57) | PTPN1PTGS2MAPK1KDM4EHSD17B10 | |
| SCHEMBL2878372 | 0.79 | KDM4E (0.57) | L3MBTL1PTPN1PTGS2MAPK1KDM4E | |
| SCHEMBL1458762 | 0.79 | HSD17B10 (0.56) | L3MBTL1PTPN1PTGS2MAPK1KDM4E | |
| SCHEMBL8117696 | 0.79 | KLK1 (0.56) | L3MBTL1GLAMAPK1KDM4EALDH1A1 | |
| SCHEMBL6200625 | 0.78 | MAPK1 (0.47) | L3MBTL1PTPN1PTGS2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |