SCHEMBL619642

SCHEMBL619642

Cc1ccc(N(c2ccccc2)c2cccc(O)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 4/20 0.52
ACHE P22303 2/20 0.47
ADRA1A P35348 4/20 0.46
CYP2C19 P33261 4/20 0.46
ADRA2A P08913 3/20 0.46
ADRA1D P25100 3/20 0.46
ADRA1B P35368 3/20 0.46
CYP2D6 P10635 3/20 0.46
ADRA2B P18089 2/20 0.46
ADRA2C P18825 2/20 0.46
LMNA P02545 2/20 0.46
OPRK1 P41145 2/20 0.46
HTR1A P08908 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
SLC6A4 P31645 1/20 0.46
HRH1 P35367 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30745213 0.96 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4ACHEADRA1A
SCHEMBL9436732 0.96 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4ACHEADRA1A
SCHEMBL2504998 0.96 ALDH1A1 (0.55) ALDH1A1TSHRCYP3A4ACHEADRA1A
SCHEMBL7654504 0.91 ACHE (0.55) ALDH1A1TSHRCYP3A4ACHEADRA1A
SCHEMBL8819150 0.90 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4ACHECYP2C19
SCHEMBL14617097 0.90 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4ACHECYP2C19
SCHEMBL7875127 0.89 ACHE (0.57) ALDH1A1TSHRCYP3A4ACHECYP2C19
SCHEMBL30415742 0.88 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4ACHECYP2C19
SCHEMBL1672628 0.88 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4ACHECYP2C19
SCHEMBL13104523 0.88 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4ACHECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103436-A A PHOTOCONDUCTIVE LAYER COMPRISING A HYDROXY FUNCTIONALIZED AROMATIC DIAMINE AND A HYDROXY FUNCTIONALIZED TRIARYLAMINE AND A CROSSLINKED POLYAMIDE MATRIX XEROX CORPORATION (US) 2000-08-15 US claimed
US-5976744-A ELECTROPHOTOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 1999-11-02 US claimed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-20210277176-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER MERCK PATENT GMBH (DE) 2021-09-09 US disclosed
US-10281831-B2 Imaging members comprising capped structured organic film compositions XEROX CORPORATION (US) 2019-05-07 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20160259256-A1 IMAGING MEMBERS COMPRISING CAPPED STRUCTURED ORGANIC FILM COMPOSITIONS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2016-09-08 US disclosed
CN-105793779-A Molecular glass mixtures for organic electronics applications 分子玻璃公司 2016-07-20 CN disclosed
US-8318892-B2 Capped structured organic film compositions XEROX CORPORATION (US) 2012-11-27 US disclosed
US-8318892-B2 Capped structured organic film compositions XEROX CORPORATION (US) 2012-11-27 US disclosed
US-8257889-B2 Imaging members comprising capped structured organic film compositions XEROX CORPORATION (US) 2012-09-04 US disclosed
US-7655373-B2 Method for imaging with imaging member having filled overcoat layer XEROX CORPORATION (US) 2010-02-02 US disclosed
US-20080096122-A1 METHOD FOR IMAGING WITH IMAGING MEMBER HAVING FILLED OVERCOAT LAYER XEROX CORPORATION (US) 2008-04-24 US disclosed
EP-1607798-A1 Imaging member having filled overcoat layer Xerox Corporation (US) 2005-12-21 EP disclosed
US-20050277036-A1 Imaging member having filled overcoat layer XEROX CORPORATION 2005-12-15 US disclosed
US-6340528-B1 USEFUL IN IONOGRAPHIC OR ELECTROPHOTOGRAPHIC APPARATUSES AND USEFUL IN HYBRID SCAVENGELESS DEVELOPMENT UNITS XEROX CORPORATION 2002-01-22 US disclosed
US-6132913-A Photoreceptor overcoatings containing hydroxy functionalized aromatic diamine, hydroxy functionalized triarylamine and crosslinked acrylated polyamide XEROX CORPORATION (US) 2000-10-17 US disclosed
US-6103436-A A PHOTOCONDUCTIVE LAYER COMPRISING A HYDROXY FUNCTIONALIZED AROMATIC DIAMINE AND A HYDROXY FUNCTIONALIZED TRIARYLAMINE AND A CROSSLINKED POLYAMIDE MATRIX XEROX CORPORATION (US) 2000-08-15 US disclosed
US-6099996-A FIRST CHARGE TRANSPORTING LAYER CONSISTS OF AROMATIC AMINE AND SECOND CHARGE TRANSPORTING LAYER CONTAINING AROMATIC AMINE WITH ARYLESTER GROUP XEROX CORPORATION (US) 2000-08-08 US disclosed
US-5976744-A ELECTROPHOTOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 1999-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 ALDH1A1 2119/4885TSHR 4586/4885CYP3A4 271/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR ALDH1A1 2965/4885TSHR 4124/4885CYP3A4 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.