Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196190 | 0.96 | ALDH1A1 (0.42) | ALDH1A1HSD17B10UCHL1OPRK1HRH2 | |
| SCHEMBL6196196 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HSD17B10UCHL1OPRK1HRH2 | |
| SCHEMBL6199632 | 0.86 | RECQL (0.47) | NPC1CCR5 | |
| SCHEMBL6197638 | 0.82 | RECQL (0.43) | CCR5 | |
| SCHEMBL6200553 | 0.80 | CCR5 (0.40) | CCR5 | |
| SCHEMBL7498995 | 0.80 | CCR5 (0.40) | CCR5 | |
| SCHEMBL6201093 | 0.80 | SLC6A2 (0.41) | ALDH1A1CCR5MEN1KMT2A | |
| SCHEMBL6199803 | 0.80 | SLC6A2 (0.41) | ALDH1A1CCR5MEN1KMT2A | |
| SCHEMBL6199172 | 0.79 | SLC6A2 (0.42) | KMT2A | |
| SCHEMBL6199797 | 0.79 | KMT2A (0.42) | ALDH1A1CCR5NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048658-B1 | ALICYCLIC ACYLATED HETEROCYCLIC DERIVATIVES | SANKYO CO (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6288059-B1 | ANTIASTHMATIC, ANTIALLERGEN AGENTS; URINARY INCONTINENCE; NATURAL KILLER CELL RECEPTOR AND TACHYKININ ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 2001-09-11 | — | — | US | disclosed |