Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043801 | 0.84 | CTSK (0.54) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL14601914 | 0.84 | CTSK (0.54) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL13043811 | 0.82 | CASP3 (0.53) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL14337553 | 0.82 | CASP3 (0.53) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL10265005 | 0.80 | CTSK (0.49) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL33525492 | 0.78 | ALDH1A1 (0.50) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL7807134 | 0.77 | GAA (0.44) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL7807139 | 0.77 | GAA (0.44) | NAAACTSLCTSBCTSKGAA | |
| SCHEMBL13017770 | 0.75 | NAAA (0.50) | NAAACTSLCTSBGAAPREP | |
| SCHEMBL12345121 | 0.75 | NAAA (0.50) | NAAACTSLCTSBGAAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |