Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850682 | 0.85 | CYP1A2 (0.40) | UGT2B7TEAD4MEN1KMT2AHDAC8 | |
| SCHEMBL6195293 | 0.84 | KDM4E (0.41) | HDAC8HDAC4HDAC2CYP2D6KDM4E | |
| SCHEMBL6199262 | 0.81 | CES2 (0.35) | TEAD4MAPTHDAC4SLC6A2SLC6A4 | |
| SCHEMBL8850424 | 0.80 | TNF (0.52) | TNFCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6196542 | 0.80 | KMT2A (0.33) | TEAD4KMT2ACYP2D6KDM4ETP53 | |
| SCHEMBL6196493 | 0.80 | KDM4E (0.34) | CYP2D6KDM4ECYP1A2TP53HTT | |
| SCHEMBL6197600 | 0.80 | KDM4E (0.37) | TEAD4MAPTKMT2ACYP2D6KDM4E | |
| SCHEMBL6196517 | 0.80 | FPR2 (0.33) | TEAD4CYP2D6KDM4ETP53HTT | |
| SCHEMBL6193968 | 0.78 | TSHR (0.47) | MAPTMEN1KMT2ANQO1TSHR | |
| SCHEMBL6194701 | 0.78 | MAPK1 (0.39) | MEN1KMT2AKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0768302-A2 | Hydroxypyridinones | Novartis AG (CH) | 1997-04-16 | — | — | EP | disclosed |