Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850201 | 0.87 | FABP4 (0.40) | FABP4FABP5PTGDR2MEN1KMT2A | |
| SCHEMBL8850424 | 0.86 | TNF (0.52) | TNFSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL6199826 | 0.85 | UGT2B7 (0.37) | CYP1A2HDAC1HDAC8MEN1KMT2A | |
| SCHEMBL8851069 | 0.82 | KDM4E (0.36) | FABP4FABP5PTGDR2KMT2ATNF | |
| SCHEMBL8850313 | 0.82 | TBXA2R (0.40) | FABP4FABP5ALDH1A1PTGDR2KMT2A | |
| SCHEMBL8850691 | 0.75 | AKR1C3 (0.37) | MEN1KMT2ATNFTEAD4SLC6A2 | |
| SCHEMBL6198182 | 0.72 | KMT2A (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8850960 | 0.70 | TNF (0.47) | CNR2TNF | |
| SCHEMBL8849907 | 0.70 | HTT (0.46) | ALDH1A1PTGDR2MEN1KMT2A | |
| SCHEMBL8850434 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATNFSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| CN-1151399-A | Novel hydroxylpyridinones | CIBA GEIGY AG (CH) | 1997-06-11 | — | — | CN | disclosed |