Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 2/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | KDM6A | O15550 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197536 | 0.88 | CYP2D6 (0.38) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6197600 | 0.86 | KDM4E (0.37) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6196493 | 0.86 | KDM4E (0.34) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6196517 | 0.86 | FPR2 (0.33) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6196542 | 0.86 | KMT2A (0.33) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6199262 | 0.84 | CES2 (0.35) | KDM4EHDAC4 | |
| SCHEMBL6198424 | 0.84 | SMN1; SMN2 (0.42) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6199826 | 0.84 | UGT2B7 (0.37) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL6197640 | 0.84 | KDM4E (0.46) | KDM4EHTTTP53CYP2D6SMN1; SMN2 | |
| SCHEMBL8850201 | 0.84 | FABP4 (0.40) | KDM4EHTTTP53CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037594-A1 | USE OF IRON CHELATING AGENT IN PREPARATION OF DRUG FOR TREATING OR PREVENTING POLYOMAVIRUS INFECTION | 上海市公共卫生临床中心 | 2022-02-24 | — | — | WO | claimed |
| CN-114073772-A | Use of an iron chelator for the treatment or prevention of polyoma viral infections | 上海市公共卫生临床中心 | 2022-02-22 | — | — | CN | claimed |
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | claimed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | claimed |
| EP-0768302-A2 | Hydroxypyridinones | Novartis AG (CH) | 1997-04-16 | — | — | EP | claimed |
| JP-9124603-A | — | — | None | — | — | JP | disclosed |
| WO-2022037594-A1 | USE OF IRON CHELATING AGENT IN PREPARATION OF DRUG FOR TREATING OR PREVENTING POLYOMAVIRUS INFECTION | 上海市公共卫生临床中心 | 2022-02-24 | — | — | WO | disclosed |
| CN-114073772-A | Use of an iron chelator for the treatment or prevention of polyoma viral infections | 上海市公共卫生临床中心 | 2022-02-22 | — | — | CN | disclosed |
| EP-0768302-B1 | Hydroxypyridinones | NOVARTIS AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-5688815-A | COMPOUNDS FOR REMOVAL OF EXCESS IRON IN MAMMALS | CIBA GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| JP-H09124603-A | NEW HYDROXYPYRIDINONE | CIBA GEIGY AG | 1997-05-13 | — | — | JP | disclosed |
| EP-0768302-A2 | Hydroxypyridinones | Novartis AG (CH) | 1997-04-16 | — | — | EP | disclosed |