Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197930 | 0.85 | POLB (0.45) | BRD4POLBMAPTKMT2ANPSR1 | |
| SCHEMBL6200591 | 0.85 | BRD4 (0.36) | BRD4POLBMAPTKMT2ANPSR1 | |
| SCHEMBL6201682 | 0.85 | GAA (0.36) | POLBMAPTACVR1BTGFBR1ACVRL1 | |
| SCHEMBL6195418 | 0.84 | TRPA1 (0.39) | MAPTNPSR1ACVR1BTGFBR1ACVRL1 | |
| SCHEMBL6667062 | 0.82 | POLB (0.37) | BRD4POLBMAPTKMT2ANPSR1 | |
| SCHEMBL6199818 | 0.79 | EGLN1 (0.40) | NPSR1LMNAEGLN1 | |
| SCHEMBL6203054 | 0.78 | EGLN1 (0.38) | NPSR1LMNAEGLN1 | |
| SCHEMBL6199949 | 0.78 | LMNA (0.39) | NPSR1LMNAEGLN1 | |
| SCHEMBL6201678 | 0.77 | GAA (0.37) | POLBMAPTACVR1BTGFBR1ACVRL1 | |
| SCHEMBL6200535 | 0.77 | EGLN1 (0.42) | POLBMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |