Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199942 | 0.86 | NR3C1 (0.39) | PPARALMNANR3C1EGLN1PPARG | |
| SCHEMBL6201682 | 0.83 | GAA (0.36) | GAAPPARAS1PR3P2RX3LMNA | |
| SCHEMBL6200591 | 0.83 | BRD4 (0.36) | GAAPPARAS1PR3P2RX3LMNA | |
| SCHEMBL6671910 | 0.81 | P2RX3 (0.36) | GAAS1PR3P2RX3LMNANR3C1 | |
| SCHEMBL6667062 | 0.79 | POLB (0.37) | GAAS1PR3P2RX3LMNANR3C1 | |
| SCHEMBL6200596 | 0.77 | BRD4 (0.37) | GAAS1PR3P2RX3LMNAEGLN1 | |
| SCHEMBL6195418 | 0.76 | TRPA1 (0.39) | GAAS1PR3P2RX3LMNANR3C1 | |
| SCHEMBL6197770 | 0.74 | PLAU (0.42) | LMNANR3C1EGLN1CNR2 | |
| SCHEMBL6198141 | 0.73 | EGLN1 (0.47) | GAALMNANR3C1EGLN1CNR2 | |
| SCHEMBL6197930 | 0.73 | POLB (0.45) | GAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |