Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620138 | 1.00 | SLC6A3 (0.38) | SLC6A3ALDH1A1NPSR1SLC6A2SLC6A4 | |
| SCHEMBL375632 | 0.83 | HIF1A (0.34) | — | |
| SCHEMBL375631 | 0.83 | HIF1A (0.34) | — | |
| SCHEMBL6286943 | 0.71 | CYP2D6 (0.49) | SLC6A3ALDH1A1 | |
| SCHEMBL3996792 | 0.69 | TP53 (0.47) | SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL6592409 | 0.69 | TP53 (0.47) | SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL12253349 | 0.69 | PTGDR (0.38) | ALDH1A1NPSR1 | |
| SCHEMBL2618028 | 0.69 | PTGDR (0.38) | ALDH1A1NPSR1 | |
| SCHEMBL8809100 | 0.68 | TSHR (0.53) | ALDH1A1 | |
| SCHEMBL14045008 | 0.67 | THRB (0.46) | SLC6A3ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8652360-B2 | Semiconductor nanocrystals | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2014-02-18 | — | — | US | disclosed |
| US-8653291-B2 | Method for surface functionalization by disubstituted alkynes | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-02-18 | — | — | US | disclosed |
| US-8592619-B2 | Bifunctional molecules comprising a cycloalkyne or heterocycloalkyne group and a redox group | Commissariat a L'Energie Atomique et aux Enerigies Alternatives (FR) | 2013-11-26 | — | — | US | disclosed |
| US-8541604-B2 | Process for the functionalization of biological molecules | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2013-09-24 | — | — | US | disclosed |
| US-20120095247-A1 | METHOD FOR SURFACE FUNCTIONALIZATION BY DISUBSTITUTED ALKYNES | COMMISSARIAT A L'ENERGIE AUTOMIQUE ET AUX ENE ALT (FR) | 2012-04-19 | — | — | US | disclosed |
| US-20120037871-A1 | NOVEL BIFUNCTIONAL MOLECULES COMPRISING A CYCLOALKYNE OR HETEROCYCLOALKYNE GROUP AND A REDOX GROUP | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20110118484-A1 | PROCESS FOR THE FUNCTIONALIZATION OF BIOLOGICAL MOLECULES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-05-19 | — | — | US | disclosed |
| US-20100200813-A1 | SEMICONDUCTOR NANOCRYSTALS | COMMISSARIAT A L' ENERGIE ATOMIQUE (FR) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120037871-A1 | NOVEL BIFUNCTIONAL MOLECULES COMPRISING A CYCLOALKYNE OR HETEROCYCLOALKYNE GROUP AND A REDOX GROUP | CBR3, CBR1, CYBB | SLC6A3 4606/4885ALDH1A1 244/4885NPSR1 3295/4885 |
| US-20110118484-A1 | PROCESS FOR THE FUNCTIONALIZATION OF BIOLOGICAL MOLECULES | POLRMT, DNASE1, POLM | SLC6A3 4518/4885ALDH1A1 597/4885NPSR1 416/4885 |
| US-20120095247-A1 | METHOD FOR SURFACE FUNCTIONALIZATION BY DISUBSTITUTED ALKYNES | F12, CYP1A1, ADGRF1 | SLC6A3 2029/4885ALDH1A1 72/4885NPSR1 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.