Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 12/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 12/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27307967 | 0.85 | SLC22A12 (0.48) | XDHSLC22A12EIF4E | |
| SCHEMBL29038974 | 0.83 | SLC22A12 (0.54) | XDHSLC22A12 | |
| SCHEMBL9256985 | 0.82 | SLC22A12 (0.56) | XDHSLC22A12 | |
| SCHEMBL5089124 | 0.77 | MAOA (0.50) | ACLYRXRARXRBRXRG | |
| SCHEMBL508503 | 0.76 | TSHR (0.57) | XDHSLC22A12FLT1FLT4KDR | |
| SCHEMBL593271 | 0.76 | ACLY (0.54) | ACLYRXRARXRB | |
| SCHEMBL3818624 | 0.75 | EIF4E (0.52) | XDHSLC22A12FLT1FLT4KDR | |
| SCHEMBL3157619 | 0.74 | XDH (0.53) | XDHSLC22A12TRPM4 | |
| SCHEMBL411720 | 0.73 | HNF4A (0.52) | RXRARXRB | |
| SCHEMBL2225438 | 0.73 | ALDH1A1 (0.57) | XDHSLC22A12FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395259-A4 | URAZOLE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2005-01-26 | — | — | EP | claimed |
| EP-1395259-A2 | URAZOLE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | Bristol-Myers Squibb Company (US) | 2004-03-10 | — | — | EP | claimed |
| WO-2002094186-A2 | URAZOLE COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-11-28 | — | — | WO | claimed |