Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.55 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203848 | 0.91 | DRD2 (0.51) | SLC5A1SLC5A2CES2CES1ACKR3 | |
| SCHEMBL6161424 | 0.91 | CES2 (0.47) | SLC5A1SLC5A2CES2CES1ACKR3 | |
| SCHEMBL31661842 | 0.79 | CES2 (0.57) | CES2CES1ACKR3POLBMEN1 | |
| SCHEMBL959448 | 0.79 | CES2 (0.57) | CES2CES1ACKR3RAB9ANPC1 | |
| SCHEMBL3527017 | 0.79 | CES2 (0.57) | CES2CES1ACKR3POLBMEN1 | |
| SCHEMBL6944180 | 0.79 | CES2 (0.57) | CES2CES1ACKR3 | |
| SCHEMBL11847285 | 0.79 | CES2 (0.57) | CES2CES1ACKR3RAB9ANPC1 | |
| SCHEMBL3907360 | 0.76 | CES2 (0.53) | CES2CES1ACKR3RAB9ANPC1 | |
| SCHEMBL9827785 | 0.76 | CES2 (0.53) | CES2CES1ACKR3RAB9ANPC1 | |
| SCHEMBL20268270 | 0.76 | CES2 (0.53) | CES2CES1ACKR3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |