Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12676322 | 0.72 | GAA (0.47) | ALDH1A1MCOLN3GAAKMT2APKM | |
| SCHEMBL12676277 | 0.72 | GAA (0.47) | ALDH1A1MCOLN3GAAKMT2APKM | |
| SCHEMBL26720612 | 0.71 | SLC6A3 (0.54) | ALDH1A1GAA | |
| SCHEMBL12296177 | 0.70 | PNMT (0.37) | ALDH1A1GAAKMT2AGRM7DAO | |
| SCHEMBL12733121 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MCOLN3GAAKMT2APKM | |
| SCHEMBL18625769 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MCOLN3GAAKMT2APKM | |
| SCHEMBL9433318 | 0.68 | SYK (0.43) | ALDH1A1MCOLN3KMT2AHPGD | |
| SCHEMBL11625723 | 0.68 | RAB9A (0.50) | ALDH1A1MCOLN3GAAKMT2APKM | |
| SCHEMBL4762196 | 0.68 | ALDH1A1 (0.46) | ALDH1A1MCOLN3GAAKMT2APKM | |
| SCHEMBL3829715 | 0.68 | ALDH1A1 (0.39) | ALDH1A1MCOLN3GAAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549278-A4 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2005-12-14 | — | — | EP | disclosed |
| EP-1549278-A2 | M sb 3 /sb MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004012684-A2 | M3MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |