Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201493 | 0.76 | LMNA (0.46) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL28731474 | 0.74 | L3MBTL1 (0.64) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL6201073 | 0.73 | CYP19A1 (0.53) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL6204074 | 0.73 | MDM2 (0.41) | FFAR2TSHR | |
| SCHEMBL26820603 | 0.72 | MGAM (0.53) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL29110671 | 0.72 | MGAM (0.53) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL7821921 | 0.71 | POLB (0.77) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL15075815 | 0.71 | POLB (0.77) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL15076001 | 0.71 | POLB (0.59) | MGAMGAASIMGAM2PDPK1 | |
| SCHEMBL15075993 | 0.71 | POLB (0.59) | MGAMGAASIMGAM2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |