Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399255 | 0.87 | CNR2 (0.31) | TRPC5 | |
| SCHEMBL6405632 | 0.85 | TRPC5 (0.39) | TRPC5 | |
| SCHEMBL6207134 | 0.81 | TUBB4A (0.37) | MAPTTRPC5 | |
| SCHEMBL6207571 | 0.78 | TRPC5 (0.40) | TRPC5 | |
| SCHEMBL6281375 | 0.73 | IDO1 (0.33) | — | |
| SCHEMBL6207184 | 0.72 | FLT1 (0.39) | TRPC5 | |
| SCHEMBL6205699 | 0.72 | MAP2K1 (0.37) | — | |
| SCHEMBL6398977 | 0.72 | KDR (0.34) | — | |
| SCHEMBL6396876 | 0.72 | FLT3 (0.37) | MAPTTDP1TRPC5 | |
| SCHEMBL6406191 | 0.71 | ALDH1A1 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578736-A1 | MEK INHIBITING OXA- AND THIA-DIAZOL-2-YL-PHENYLAMINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-09-28 | — | — | EP | claimed |
| WO-2004056789-A1 | MEK INHIBITING OXA- AND THIA-DIAZOL-2-YL PHENYLAMINE DERIVATES | WARNER-LAMBERT COMPANY LLC (US) | 2004-07-08 | — | — | WO | claimed |