Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.85 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.85 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | RAD52 | P43351 | 2/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.64 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CCR6 | P51684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441990 | 0.97 | PABPC1 (0.87) | FTOPABPC1POLBRAD52NR1I2 | |
| Mitonafide SCHEMBL29352711 | 0.92 | FTO (1.00) | FTOPABPC1POLBRAD52NR1I2 | |
| Mitonafide SCHEMBL62046 | 0.92 | FTO (1.00) | FTOPABPC1POLBRAD52NR1I2 | |
| Mitonafide SCHEMBL29499462 | 0.92 | FTO (1.00) | FTOPABPC1POLBRAD52NR1I2 | |
| Mitonafide SCHEMBL5166813 | 0.91 | FTO (0.98) | FTOPABPC1POLBRAD52NR1I2 | |
| SCHEMBL9501524 | 0.88 | FTO (0.80) | FTOPABPC1POLBRAD52NR1I2 | |
| SCHEMBL9504075 | 0.87 | FTO (0.87) | FTOPABPC1POLBRAD52NR1I2 | |
| SCHEMBL14560564 | 0.86 | FTO (0.73) | FTOPABPC1POLBRAD52NR1I2 | |
| Mitonafide SCHEMBL5781995 | 0.86 | FTO (0.88) | FTOPABPC1POLBRAD52NR1I2 | |
| SCHEMBL11441587 | 0.86 | PABPC1 (0.72) | FTOPABPC1POLBRAD52NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | AUCKLAND UNISERVICES LIMITED | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173332-A1 | Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds | BLVRB, POR, CBR3 | FTO 364/4885PABPC1 2431/4885POLB 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.