Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.87 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.87 |
| ▸ | POLB | P06746 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAD52 | P43351 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HEXA | P06865 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501524 | 0.96 | FTO (0.80) | FTOPABPC1POLBMEN1KMT2A | |
| Mitonafide SCHEMBL62046 | 0.93 | FTO (1.00) | FTOPABPC1POLBMEN1KMT2A | |
| Mitonafide SCHEMBL29499462 | 0.93 | FTO (1.00) | FTOPABPC1POLBMEN1KMT2A | |
| Mitonafide SCHEMBL29352711 | 0.93 | FTO (1.00) | FTOPABPC1POLBMEN1KMT2A | |
| Mitonafide SCHEMBL5166813 | 0.92 | FTO (0.98) | FTOPABPC1POLBMEN1KMT2A | |
| SCHEMBL8984522 | 0.92 | FTO (0.74) | FTOPABPC1POLBMEN1KMT2A | |
| SCHEMBL11441990 | 0.88 | PABPC1 (0.87) | FTOPABPC1POLBMEN1KMT2A | |
| SCHEMBL11550721 | 0.88 | FTO (0.79) | FTOPABPC1POLBMEN1KMT2A | |
| SCHEMBL2989147 | 0.87 | FTO (0.85) | FTOPABPC1POLBMEN1KMT2A | |
| Mitonafide SCHEMBL5781995 | 0.87 | FTO (0.88) | FTOPABPC1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281902-B1 | BIS-NAPHTHALIMIDES, THEIR PREPARATION AND USE | KNOLL AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4874863-A | Bisnaphthalimides | KNOLL AG (DE) | 1989-10-17 | — | — | US | disclosed |