Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677464 | 0.82 | LMNA (0.48) | POLBALDH1A1LMNA | |
| SCHEMBL27396351 | 0.81 | ALDH1A1 (0.41) | SIRT2SIRT3SIRT1RAB9AMGLL | |
| SCHEMBL18752265 | 0.80 | APP (0.45) | RAB9AAPPALDH1A1 | |
| SCHEMBL27621158 | 0.79 | MGLL (0.45) | RAB9AMGLLENPP2 | |
| SCHEMBL28309370 | 0.79 | SIRT2 (0.52) | SIRT2RAB9AMGLLENPP2 | |
| SCHEMBL6648255 | 0.78 | ALDH1A1 (0.43) | RAB9APOLBALDH1A1LMNA | |
| SCHEMBL7656159 | 0.78 | IDO1 (0.59) | POLBPARP1 | |
| SCHEMBL26992213 | 0.78 | FFAR1 (0.43) | RAB9APOLBALDH1A1LMNA | |
| SCHEMBL14148255 | 0.78 | CSNK2A1 (0.48) | SIRT2SIRT3SIRT1POLBALDH1A1 | |
| SCHEMBL20109593 | 0.76 | ENPP2 (0.52) | ALDH1A1LMNANOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116911-A1 | ANTI-FRα ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |