Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.81 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.81 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.81 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.64 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515748 | 0.86 | KMT2A (0.70) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205955 | 0.85 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205956 | 0.85 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6205953 | 0.85 | CASP3 (0.61) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL4101284 | 0.85 | PGR (0.78) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL1025444 | 0.85 | CASP3 (0.67) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL1025441 | 0.85 | CASP3 (0.67) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL1792614 | 0.83 | KMT2A (0.72) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL6831091 | 0.83 | CASP3 (0.59) | CASP3SENP8SENP7SENP6KMT2A | |
| SCHEMBL30927031 | 0.82 | CASP3 (0.89) | CASP3SENP8SENP7SENP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831800-A4 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-03-10 | — | — | EP | disclosed |
| US-5741819-A | THROMBOSIS INHIBITORS; ANTIINFLAMMATORY AGENTS; NEURODEGENERATIVE DISORDERS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0831800-A1 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040100-A1 | ARYLSULFONYLAMINOBENZENE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |