Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 7/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205393 | 0.80 | HDAC1 (0.35) | XDHHDAC1HDAC6NR1H2 | |
| SCHEMBL4590751 | 0.80 | ADH1A (0.36) | HDAC1HDAC6 | |
| SCHEMBL6205186 | 0.79 | P4HB (0.47) | XDHFBP1 | |
| SCHEMBL7954292 | 0.78 | ADH1A (0.32) | HDAC1HDAC6NR1H2 | |
| SCHEMBL3558952 | 0.73 | ADH1A (0.47) | HDAC1HDAC6 | |
| SCHEMBL5623265 | 0.72 | P4HB (0.47) | XDHFBP1 | |
| SCHEMBL6618596 | 0.71 | ADH1A (0.46) | XDH | |
| SCHEMBL7092620 | 0.71 | SRD5A2 (0.42) | — | |
| SCHEMBL6852340 | 0.70 | ADH1A (0.44) | — | |
| SCHEMBL12596983 | 0.68 | ADH1A (0.38) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938474-B1 | CYCLOPROPYLINDOLE COMPOUNDS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LTD (NZ) | 2005-11-23 | — | — | EP | disclosed |
| US-6130237-A | Condensed N-aclyindoles as antitumor agents | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-10-10 | — | — | US | disclosed |