Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 4/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177185 | 0.89 | LMNA (0.41) | CCR9LMNALIPE | |
| SCHEMBL6173841 | 0.89 | LIPE (0.41) | CCR9LMNALIPE | |
| SCHEMBL6175499 | 0.87 | LMNA (0.37) | CCR9LMNALIPE | |
| SCHEMBL6176639 | 0.87 | OXTR (0.36) | CCR9LMNA | |
| SCHEMBL6173101 | 0.87 | LMNA (0.38) | CCR9LMNALIPE | |
| SCHEMBL6173186 | 0.85 | LMNA (0.40) | CCR9LMNALIPE | |
| SCHEMBL6172197 | 0.84 | LMNA (0.40) | CCR9LMNALIPE | |
| SCHEMBL6176663 | 0.83 | LMNA (0.39) | LMNA | |
| SCHEMBL6175831 | 0.83 | NPC1 (0.46) | LMNA | |
| SCHEMBL6173298 | 0.83 | LMNA (0.39) | CCR9LMNALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |