Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205203 | 0.84 | CES2 (0.43) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL11466035 | 0.83 | ALDH1A1 (0.44) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL10459782 | 0.82 | CXCL8 (0.43) | CYP1A2ACP3ALDH1A1KMT2ACXCL8 | |
| SCHEMBL365284 | 0.82 | MEN1 (0.46) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL8128086 | 0.82 | MEN1 (0.46) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL5112227 | 0.82 | MEN1 (0.46) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL11578728 | 0.79 | ACP3 (0.47) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL1244293 | 0.77 | SRC (0.50) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL5389348 | 0.76 | CYP1A2 (0.54) | CYP1A2ACP3ALDH1A1MEN1KMT2A | |
| SCHEMBL7825123 | 0.76 | CYP1A2 (0.54) | CYP1A2ALDH1A1CES2CES1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098891-B1 | POLYCYCLIC THIAZOLIDIN-2-YLIDENE AMINES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| EP-1098891-A1 | POLYCYCLIC THIAZOLIDIN-2-YLIDENE AMINES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Aventis Pharma Deutschland GmbH (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-6159996-A | Polycyclic thiazolidin-2-ylidene amines, process for their preparation, and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-12 | — | — | US | disclosed |
| WO-2000004006-A1 | POLYCYCLIC THIAZOLIDIN-2-YLIDENE AMINES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999033813-A1 | 3-HYDROXY-PYRAZOLE FUNGICIDAL DERIVATIVES | AVENTIS CROPSCIENCE S.A.; (FR) | 1999-07-08 | — | — | WO | disclosed |