Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466780 | 0.82 | CXCL8 (0.44) | CXCL8ACP3AOC3IDO1TDO2 | |
| SCHEMBL6207207 | 0.82 | CYP1A2 (0.54) | CXCL8ACP3IDO1TDO2IDO2 | |
| SCHEMBL6205203 | 0.82 | CES2 (0.43) | ACP3AOC3IDO1TDO2IDO2 | |
| SCHEMBL9518776 | 0.79 | CXCL8 (0.47) | CXCL8ACP3AOC3IDO1TDO2 | |
| SCHEMBL11466035 | 0.78 | ALDH1A1 (0.44) | ACP3IDO1TDO2IDO2CYP1A2 | |
| SCHEMBL23300492 | 0.76 | CXCL8 (0.45) | CXCL8ACP3AOC3IDO1TDO2 | |
| SCHEMBL2838988 | 0.76 | CXCL8 (0.45) | CXCL8ACP3AOC3IDO1TDO2 | |
| SCHEMBL5065343 | 0.76 | CASP1 (0.49) | CXCL8ACP3AOC3IDO1TDO2 | |
| SCHEMBL18547605 | 0.76 | CXCL8 (0.45) | CXCL8ACP3AOC3IDO1TDO2 | |
| SCHEMBL6314766 | 0.76 | CXCL8 (0.45) | CXCL8ACP3AOC3IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923870-A | 2-Carbonyl substituted N,N'-di-(trimethoxygenzoyl)piperazines, process for preparing the same and therapeutical compounds containing them | Societe de Conseils de Reserches et d'Applications Scientifiques (FR) | 1990-05-08 | — | — | US | disclosed |