Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588199 | 0.89 | HSD17B10 (0.50) | HSD17B10LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16178490 | 0.80 | MAPT (0.49) | MEN1KMT2AHSD17B10HTTSMN1; SMN2 | |
| SCHEMBL2564898 | 0.80 | NPC1 (0.46) | MEN1KMT2AHSD17B10SMN1; SMN2GAA | |
| SCHEMBL8199494 | 0.79 | MAOB (0.46) | MEN1KMT2AGPR183LMNAGAA | |
| SCHEMBL8840747 | 0.79 | SIGMAR1 (0.44) | MEN1KMT2AHSD17B10LMNAALDH1A1 | |
| SCHEMBL8196750 | 0.79 | G6PC1 (0.49) | MEN1KMT2AHSD17B10DRD4 | |
| SCHEMBL8207604 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL3410482 | 0.76 | MAOA (0.56) | MEN1KMT2AHSD17B10LMNAHTT | |
| SCHEMBL6680147 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL5253949 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2ALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551844-A2 | ANTITUMORAL ANALOGS OF LAMELLARINS | Pharma Mar, S.A.U. (ES) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004014917-A2 | ANTITUMORAL ANALOGS OF LAMELLARINS | PHARMA MAR, S.A.U. (ES) | 2004-02-19 | — | — | WO | disclosed |
| EP-1287004-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF AN ECTEINASCIDIN COMPOUND | PHARMA MAR, S.A. (ES) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087895-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF AN ECTEINASCHIDIN COMPOUND | PHARMA MAR, S.A. (ES) | 2001-11-22 | — | — | WO | disclosed |
| US-4544662-A | ALDOSE REDUCTASE INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1985-10-01 | — | — | US | disclosed |
| EP-0094184-A1 | Indoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-11-16 | — | — | EP | disclosed |