Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210370 | 0.86 | FKBP1A (0.41) | TSHRALDH1A1SMYD3CYP2C19FKBP1A | |
| SCHEMBL6208973 | 0.86 | TBXAS1 (0.35) | HPGDALDH1A1MAPK1 | |
| SCHEMBL4038371 | 0.86 | KDM4E (0.40) | KDM4EHPGDTSHRHSD17B10ALDH1A1 | |
| SCHEMBL6208666 | 0.85 | KDM4E (0.39) | KDM4EHPGDTSHRHSD17B10ALDH1A1 | |
| SCHEMBL6208517 | 0.85 | HSD17B10 (0.41) | KDM4EHPGDTSHRHSD17B10ALDH1A1 | |
| SCHEMBL6209393 | 0.82 | CTSL (0.36) | SMYD3 | |
| SCHEMBL6211364 | 0.81 | DPP4 (0.45) | ALDH1A1SMYD3CYP3A4CYP2C19 | |
| SCHEMBL6212946 | 0.80 | RAB9A (0.47) | ALDH1A1SMYD3GAAMAPK1 | |
| SCHEMBL6212092 | 0.80 | PREP (0.48) | TSHRALDH1A1CYP3A4GAA | |
| SCHEMBL5941964 | 0.80 | PKM (0.38) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |