Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211558 | 0.93 | LMNA (0.38) | LMNAHSD17B10SMYD3ALDH1A1ELOVL6 | |
| SCHEMBL6212436 | 0.93 | LMNA (0.38) | LMNAHSD17B10SMYD3ALDH1A1RAB9A | |
| SCHEMBL6211403 | 0.92 | NAMPT (0.37) | LMNAHSD17B10SMYD3ELOVL6DPP4 | |
| SCHEMBL6209651 | 0.92 | LMNA (0.42) | LMNAELOVL6POLBKMT2ADPP4 | |
| SCHEMBL6213162 | 0.92 | CTSK (0.42) | LMNAHSD17B10SMYD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL6211427 | 0.91 | ALDH1A1 (0.36) | LMNAHSD17B10SMYD3ALDH1A1RAB9A | |
| SCHEMBL6211355 | 0.91 | LMNA (0.36) | LMNAHSD17B10SMYD3ALDH1A1ELOVL6 | |
| SCHEMBL6211220 | 0.91 | CHRM4 (0.38) | LMNAHSD17B10ALDH1A1RAB9AELOVL6 | |
| SCHEMBL6208961 | 0.91 | CTSK (0.38) | LMNAHSD17B10ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6209110 | 0.90 | HSD17B10 (0.39) | LMNAHSD17B10SMYD3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |