Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208982 | 0.97 | ALDH1A1 (0.44) | CYP2A6ALDH1A1MAPK1HPGDHTR2C | |
| SCHEMBL4326011 | 0.88 | CYP2A6 (0.50) | CYP2A6ALDH1A1MAPK1HPGDHTR2C | |
| SCHEMBL21855095 | 0.78 | CYP2A6 (0.44) | CYP2A6ALDH1A1MAPK1HPGDHTR2C | |
| SCHEMBL218474 | 0.72 | LMNA (0.44) | CYP2A6ALDH1A1HPGDHTR2CRAB9A | |
| SCHEMBL2537130 | 0.72 | MAPK14 (0.45) | KMT2ARAB9ANPC1GALR1 | |
| SCHEMBL4555821 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPK1HPGDMAPTKMT2A | |
| SCHEMBL6100514 | 0.72 | ACHE (0.44) | ALDH1A1MAPK1HPGDMAPTGALR1 | |
| SCHEMBL8310754 | 0.72 | TRPA1 (0.40) | ALDH1A1 | |
| SCHEMBL1673427 | 0.71 | ALDH1A1 (0.73) | CYP2A6ALDH1A1MAPK1MAPTKMT2A | |
| SCHEMBL68094 | 0.71 | ALDH1A1 (0.73) | CYP2A6ALDH1A1MAPK1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4118086-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | Fochon Biosciences, Ltd. (CN) | 2023-01-18 | — | — | EP | disclosed |
| WO-2021180107-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-09-16 | — | — | WO | disclosed |
| EP-1507763-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | Bayer HealthCare AG (DE) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003097607-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-11-27 | — | — | WO | disclosed |