Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443432 | 0.78 | CA2 (0.35) | CA2TSHRUSP2 | |
| SCHEMBL3241100 | 0.72 | CA2 (0.36) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL21268867 | 0.71 | CA1 (0.33) | CA2TSHR | |
| Lithium Ion SCHEMBL21269967 | 0.71 | CA1 (0.33) | CA2TSHR | |
| SCHEMBL18152013 | 0.71 | CA1 (0.33) | CA2TSHR | |
| SCHEMBL21269991 | 0.71 | CA1 (0.33) | CA2TSHR | |
| SCHEMBL21269234 | 0.71 | CA2 (0.39) | CA2TSHRCYP3A4NFKB1NPSR1 | |
| SCHEMBL21269567 | 0.71 | CA1 (0.33) | CA2TSHR | |
| Potassium Ion SCHEMBL21268954 | 0.71 | CA4 (0.37) | CA2TSHR | |
| SCHEMBL2454759 | 0.71 | CA2 (0.32) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220356307-A1 | VULCANISABLE SILICONE COMPOSITIONS | DOW SILICONES CORP (US) | 2022-11-10 | — | — | US | disclosed |
| US-20120039837-A1 | Hair-Treatment Compositions with Corneocyte Proteins or Polypeptides and Silicone(s) | SOMFLETH PETRA (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20080152604-A1 | SKIN-LIGHTENING COMPOSITIONS WITH AN IMPROVED ACTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-06-26 | — | — | US | disclosed |
| US-20070292378-A1 | Hair-treatment compositions with corneocyte proteins or polypeptides and silicone(s) | HENKEL AG & CO. KGAA (DE) | 2007-12-20 | — | — | US | disclosed |
| EP-0802222-A1 | Method of adhesion improvement for silicone compositions | DOW CORNING CORPORATION (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0236043-B1 | IMPROVED ROOM-TEMPERATURE CURING SILICONE SEALANTS | DOW CORNING CORPORATION (US) | 1992-06-03 | — | — | EP | disclosed |
| EP-0236043-A2 | Improved room-temperature curing silicone sealants | DOW CORNING CORPORATION (US) | 1987-09-09 | — | — | EP | disclosed |
| US-4652624-A | IMPROVING OIL SWELL RESISTANCE AND SHELF LIFE | DOW CORNING CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292378-A1 | Hair-treatment compositions with corneocyte proteins or polypeptides and silicone(s) | CUTA, KRT18, PLOD3 | CA2 3598/4885TSHR 2089/4885CYP3A4 4758/4885 |
| US-20120039837-A1 | Hair-Treatment Compositions with Corneocyte Proteins or Polypeptides and Silicone(s) | CUTA, KRT18, PLOD3 | CA2 3598/4885TSHR 2089/4885CYP3A4 4758/4885 |
| US-20080152604-A1 | SKIN-LIGHTENING COMPOSITIONS WITH AN IMPROVED ACTION | ALAD, TYR, CYP24A1 | CA2 549/4885TSHR 3449/4885CYP3A4 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.