Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811 | 0.89 | MMP2 (0.54) | MEN1KMT2AMMP2MMP9FFAR1 | |
| SCHEMBL5797 | 0.86 | EPHX2 (0.53) | MAOBADAMTS4MMP13FFAR1FFAR4 | |
| SCHEMBL6158 | 0.85 | LTA4H (0.46) | MMP2MMP9ADAMTS4MMP13FFAR1 | |
| SCHEMBL5636 | 0.81 | MMP2 (0.56) | MAOBMMP2MMP9FFAR1FFAR4 | |
| SCHEMBL6073 | 0.78 | L3MBTL1 (0.56) | MEN1KMT2AFFAR1 | |
| SCHEMBL11898793 | 0.78 | CYP4F2 (0.51) | MEN1KMT2AADAMTS4MMP13 | |
| SCHEMBL11899994 | 0.77 | LTA4H (0.61) | FFAR1 | |
| SCHEMBL18002977 | 0.77 | MAOB (0.63) | MAOBFFAR1FFAR4SLC6A5 | |
| SCHEMBL12049 | 0.77 | LTA4H (0.50) | FFAR1 | |
| SCHEMBL15453908 | 0.75 | CA12 (0.47) | MAOBMMP2MMP9MMP13FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |