Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217122 | 0.82 | KDM1A (0.34) | EPHX2 | |
| SCHEMBL6982209 | 0.78 | EPHX2 (0.36) | EPHX2PRMT5WDR77 | |
| SCHEMBL6218423 | 0.77 | CAMKK2 (0.30) | — | |
| SCHEMBL6211091 | 0.75 | EPHX2 (0.34) | EPHX2PRMT5WDR77 | |
| SCHEMBL6978487 | 0.73 | ESR2 (0.44) | EPHX2PRMT5WDR77 | |
| SCHEMBL788535 | 0.73 | QDPR (0.45) | EPHX2 | |
| SCHEMBL6213577 | 0.72 | CYP2C9 (0.43) | — | |
| SCHEMBL4301270 | 0.72 | SLC18A3 (0.48) | EPHX2 | |
| SCHEMBL3827824 | 0.72 | EPHX2 (0.38) | EPHX2PRMT5WDR77 | |
| SCHEMBL6214833 | 0.70 | ALDH1A1 (0.40) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379246-A4 | NOCICEPTIN ANALOGS | EURO CELTIQUE SA (LU) | 2005-09-28 | — | — | EP | claimed |
| EP-1379246-A1 | NOCICEPTIN ANALOGS | Euro-Celtique S.A. (LU) | 2004-01-14 | — | — | EP | claimed |
| WO-2002085357-A1 | NOCICEPTIN ANALOGS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | claimed |
| EP-1379246-A4 | NOCICEPTIN ANALOGS | EURO CELTIQUE SA (LU) | 2005-09-28 | — | — | EP | disclosed |
| EP-1379246-A1 | NOCICEPTIN ANALOGS | Euro-Celtique S.A. (LU) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002085357-A1 | NOCICEPTIN ANALOGS | EURO-CELTIQUE, S.A. (LU) | 2002-10-31 | — | — | WO | disclosed |