Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | FPR1 | P21462 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213918 | 0.88 | MPO (0.63) | MPOMAPTALDH1A1ENPP1LMNA | |
| SCHEMBL6211513 | 0.87 | MPO (0.77) | MPOMAPTALDH1A1ENPP1LMNA | |
| SCHEMBL16208352 | 0.86 | THRB (0.67) | MPOMAPTALDH1A1ENPP1THRB | |
| SCHEMBL15347348 | 0.85 | MPO (1.00) | MPOMAPTALDH1A1THRBLMNA | |
| SCHEMBL16208411 | 0.84 | KCNH2 (0.64) | MPOMAPTALDH1A1ENPP1LMNA | |
| SCHEMBL6213951 | 0.82 | ALDH1A1 (0.64) | MPOMAPTALDH1A1LMNAPOLB | |
| SCHEMBL17531756 | 0.82 | MPO (0.73) | MPOMAPTALDH1A1ENPP1THRB | |
| SCHEMBL16208440 | 0.81 | MPO (0.71) | MPOMAPTALDH1A1THRBLMNA | |
| SCHEMBL17531772 | 0.80 | ENPP1 (0.68) | MPOMAPTALDH1A1ENPP1LMNA | |
| SCHEMBL17712421 | 0.78 | MAPT (0.69) | MPOMAPTALDH1A1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | claimed |
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | disclosed |