Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.63 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213918 | 0.84 | MPO (0.63) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL6212573 | 0.82 | MPO (0.73) | ALDH1A1MAPTLMNAPOLBPKM | |
| SCHEMBL6211513 | 0.81 | MPO (0.77) | ALDH1A1MAPTLMNAMAPK1POLB | |
| SCHEMBL17624909 | 0.79 | MAPT (0.83) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL16208428 | 0.78 | MAPT (0.78) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL16208411 | 0.78 | KCNH2 (0.64) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL14970868 | 0.75 | PTPN1 (0.76) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL7771185 | 0.75 | PTPN1 (0.76) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL16208352 | 0.75 | THRB (0.67) | ALDH1A1PRMT5WDR77MAPTLMNA | |
| SCHEMBL12486391 | 0.73 | MPO (1.00) | ALDH1A1PRMT5WDR77MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | claimed |
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | disclosed |