Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212573 | 0.87 | MPO (0.73) | MPOSMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL6213918 | 0.87 | MPO (0.63) | MPOSMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL16208435 | 0.83 | MPO (0.73) | MPOSMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL6213951 | 0.81 | ALDH1A1 (0.64) | MPOSMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL16208389 | 0.80 | MPO (0.72) | MPOSMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL16208411 | 0.78 | KCNH2 (0.64) | MPOSMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL16208352 | 0.78 | THRB (0.67) | MPOLMNAMAPK1MAPTMEN1 | |
| SCHEMBL9693079 | 0.75 | RAB9A (0.60) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL12486415 | 0.74 | MPO (0.77) | MPOSMN1; SMN2LMNAMAPK1MAPT | |
| SCHEMBL15347348 | 0.74 | MPO (1.00) | MPOSMN1; SMN2LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | claimed |
| EP-1020451-B1 | ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2005-06-15 | — | — | EP | disclosed |