Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210303 | 0.92 | NPC1 (0.47) | RAB9ANPC1LMNAALDH1A1PKM | |
| SCHEMBL6210120 | 0.92 | GAA (0.38) | RAB9ANPC1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6213495 | 0.91 | GAA (0.37) | RAB9ANPC1LMNAALDH1A1PKM | |
| SCHEMBL6208915 | 0.90 | RORC (0.39) | RAB9ACHRM4GAATSHR | |
| SCHEMBL6211360 | 0.90 | CHRM4 (0.40) | MAPK14RAB9ANPC1CHRM4LMNA | |
| SCHEMBL6213867 | 0.88 | CHRM4 (0.40) | CHRM4LMNA | |
| SCHEMBL6212649 | 0.88 | NPC1 (0.40) | MAPK14NPC1GAATSHRKMT2A | |
| SCHEMBL6210763 | 0.86 | ROCK2 (0.36) | RAB9ANPC1GAATSHR | |
| SCHEMBL6210847 | 0.85 | KEAP1 (0.38) | ALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL6211220 | 0.84 | CHRM4 (0.38) | RAB9ANPC1CHRM4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |