Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210120 | 0.94 | GAA (0.38) | GAATSHRNAMPTNPC1RAB9A | |
| SCHEMBL6208915 | 0.92 | RORC (0.39) | GAATSHRNAMPTRAB9ACTSK | |
| SCHEMBL6212682 | 0.91 | MAPK14 (0.42) | GAATSHRNPC1RAB9ALMNA | |
| SCHEMBL6212649 | 0.90 | NPC1 (0.40) | GAATSHRNAMPTNPC1KMT2A | |
| SCHEMBL6210303 | 0.90 | NPC1 (0.47) | GAATSHRNPC1RAB9ALMNA | |
| SCHEMBL6210763 | 0.87 | ROCK2 (0.36) | GAATSHRNAMPTNPC1RAB9A | |
| SCHEMBL6210847 | 0.84 | KEAP1 (0.38) | GAATSHRALDH1A1 | |
| SCHEMBL6211016 | 0.83 | CTSK (0.37) | CTSK | |
| SCHEMBL6209876 | 0.83 | CTSK (0.42) | NAMPTNPC1RAB9ALMNAMEN1 | |
| SCHEMBL6212436 | 0.83 | LMNA (0.38) | TSHRNPC1RAB9ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |