Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210120 | 0.92 | GAA (0.38) | GAACTSKTSHRDPP4NAMPT | |
| SCHEMBL6213495 | 0.92 | GAA (0.37) | GAACTSKTSHRNAMPTRAB9A | |
| SCHEMBL6210303 | 0.90 | NPC1 (0.47) | GAATSHRRAB9A | |
| SCHEMBL6212682 | 0.90 | MAPK14 (0.42) | GAATSHRCHRM4RAB9A | |
| SCHEMBL6211626 | 0.89 | CCR5 (0.38) | RORCCCR5CTSKDPP4CHRM4 | |
| SCHEMBL6212649 | 0.89 | NPC1 (0.40) | GAATSHRMCHR1NAMPT | |
| SCHEMBL6210338 | 0.87 | DPP4 (0.46) | RORCGAATSHRDPP4NAMPT | |
| SCHEMBL6211570 | 0.87 | SLC6A5 (0.38) | RORCCCR5CHRM4NAMPT | |
| SCHEMBL6210763 | 0.86 | ROCK2 (0.36) | GAATSHRNAMPTRAB9A | |
| SCHEMBL6210543 | 0.83 | CTSK (0.44) | RORCCCR5CTSKDPP4CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |