SCHEMBL621539

SCHEMBL621539

CC(C)CC1C(=O)OC(C(C)C)C(=O)N(C)C(CC(C)C)C(=O)OC(C(C)C)C(=O)N(C)C(CC(C)C)C(=O)OC(C(C)C)C(=O)N1C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 11/20 0.39
HDAC6 Q9UBN7 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14134043 1.00 ABCB1 (0.39) ABCB1HDAC6
SCHEMBL30932702 1.00 ABCB1 (0.39) ABCB1HDAC6
SCHEMBL17520705 0.92 ABCB1 (0.35) ABCB1HDAC6
SCHEMBL17520671 0.86 ABCB1 (0.33) ABCB1
SCHEMBL17520691 0.86 ABCB1 (0.37) ABCB1HDAC6
SCHEMBL17520706 0.85 ABCB1 (0.53) ABCB1HDAC6
SCHEMBL17520687 0.85 ABCB1 (0.53) ABCB1HDAC6
SCHEMBL17520513 0.82 ABCB1 (0.39) ABCB1
SCHEMBL17520709 0.76 ABCB1 (0.45) ABCB1HDAC6
SCHEMBL17520693 0.76 ABCB1 (0.49) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106434718-B Method for obtaining non-ribosomal polypeptide active product 杭州唯铂莱生物科技有限公司 2024-07-26 CN disclosed
US-20240174718-A1 RYANODINE RECEPTOR INHIBITOR COMPOUNDS AND METHODS RELATING THERETO VANDERBILT UNIVERSITY 2024-05-30 US disclosed
US-10738316-B2 Process for producing chimeric cyclooligodepsipeptides in filamentous fungi Technische Universität Berlin (DE) 2020-08-11 US disclosed
EP-2812005-B1 POLYHYDROXYLATED PENTACYCLIC TRITERPENE ACIDS AS HMG-COA REDUCTASE INHIBITORS PRAIRIE BERRY EUROPE GMBH (DE) 2018-06-27 EP disclosed
EP-3119900-B1 METHOD FOR OBTAINING NONRIBOSOMAL PEPTIDES BY HETEROLOGOUS EXPRESSION OF AT LEAST ONE NONRIBOSOMAL PEPTIDE SYNTHETASE IN ASPERGILLUS NIGER UNIV BERLIN TECH (DE) 2018-05-09 EP disclosed
US-20170137832-A1 PROCESS FOR PRODUCING CHIMERIC CYCLOOLIGODEPSIPEPTIDES IN FILAMENTOUS FUNGI TECHNISCHE UNIVERSITAET BERLIN (DE) 2017-05-18 US disclosed
CN-106434718-A Non ribosomal polypeptide active product capturing method 杭州唯铂莱生物科技有限公司 2017-02-22 CN disclosed
EP-3119900-A2 METHOD FOR OBTAINING MICROBIAL SECONDARY METABOLITES OR DERIVATIVES THEREOF BY HETEROLOGOUS EXPRESSION OF AT LEAST ONE SYNTHETASE OF SAID SECONDARY METABOLITES IN FILAMENTOUS FUNGI Technische Universität Berlin (DE) 2017-01-25 EP disclosed
EP-2509967-B1 NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES BAYER IP GMBH (DE) 2016-02-17 EP disclosed
WO-2015140315-A2 METHOD FOR OBTAINING MICROBIAL SECONDARY METABOLITES OR DERIVATIVES THEREOF BY HETEROLOGOUS EXPRESSION OF AT LEAST ONE SYNTHETASE OF SAID SECONDARY METABOLITES IN FILAMENTOUS FUNGI Technische Universität Berlin (DE) 2015-09-24 WO disclosed
US-20130237415-A1 SAFENER COMPOSITIONS AND METHODS FOR REDUCING MYCOTOXINS SYNGENTA CROP PROTECTION LLC (US) 2013-09-12 US disclosed
EP-2592931-A1 SAFENER COMPOSITIONS AND METHODS FOR REDUCING MYCOTOXINS Syngenta Participations AG (CH) 2013-05-22 EP disclosed
US-20120302496-A1 NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-11-29 US disclosed
EP-2509967-A1 NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES Bayer Intellectual Property GmbH (DE) 2012-10-17 EP disclosed
WO-2012021250-A1 SAFENER COMPOSITIONS AND METHODS FOR REDUCING MYCOTOXINS SYNGENTA PARTICIPATIONS AG (CH) 2012-02-16 WO disclosed
WO-2011069995-A1 NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES BAYER ANIMAL HEALTH GMBH (DE) 2011-06-16 WO disclosed
US-20080167444-A1 Abc Transporter Inhibitor SUNTORY LIMITED (JP) 2008-07-10 US disclosed
EP-1721901-A1 ABC TRANSPORTER INHIBITOR SUNTORY LIMITED (JP) 2006-11-15 EP disclosed
US-5747448-A ANTHELMINTICS MEIJI SEIKA KAISHA, LTD. (JP) 1998-05-05 US disclosed
EP-0685469-A1 PF1022 DERIVATIVE, CYCLIC DEPSIPEPTIDE MEIJI SEIKA KAISHA LTD. (JP) 1995-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174718-A1 RYANODINE RECEPTOR INHIBITOR COMPOUNDS AND METHODS RELATING THERETO RYR2, RYR1, ATP2A2 ABCB1 888/4885HDAC6 4012/4885
US-20120302496-A1 NOVEL 24-MEMBERED CYCLOOCTADEPSIPEPTIDES FROM FUNGAL STRAINS AND THEIR USE AS ANTHELMINTICS OR ENDOPARASITICIDES TOP2B, XRN2, LONP1 ABCB1 257/4885HDAC6 1813/4885
US-20080167444-A1 Abc Transporter Inhibitor SLC47A1, ABCC1, SLC47A2 ABCB1 4/4885HDAC6 2023/4885
US-10738316-B2 Process for producing chimeric cyclooligodepsipeptides in filamentous fungi COASY, ERG28, FDPS ABCB1 4107/4885HDAC6 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.