Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221617 | 0.87 | ALDH1A1 (0.36) | TRPV4KMT2AALDH1A1HSD17B10 | |
| SCHEMBL6217886 | 0.85 | ACHE (0.39) | KMT2AALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL6214821 | 0.85 | ITGB3 (0.40) | F10 | |
| SCHEMBL4313283 | 0.79 | F10 (0.53) | F10KMT2AALDH1A1HPGD | |
| SCHEMBL6216452 | 0.79 | CHRM3 (0.42) | — | |
| SCHEMBL6215362 | 0.78 | F10 (0.39) | F10KMT2AALDH1A1GAAHPGD | |
| SCHEMBL5781421 | 0.78 | F10 (0.42) | F10KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL5777471 | 0.77 | F10 (0.48) | F10POLBKMT2AALDH1A1 | |
| SCHEMBL6215019 | 0.76 | KMT2A (0.42) | POLBKMT2AALDH1A1GAAHPGD | |
| SCHEMBL5779074 | 0.76 | F10 (0.45) | F10KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414817-B1 | substituted isoindoles and the use thereof | BAYER HEALTHCARE AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-1414817-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | Bayer HealthCare AG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011858-A1 | SUBSTITUTED ISOINDOLES AND E USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-02-13 | — | — | WO | disclosed |