Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221255 | 0.80 | ALDH1A1 (0.36) | IKBKB | |
| SCHEMBL6220507 | 0.80 | GRM2 (0.31) | IKBKB | |
| SCHEMBL6220260 | 0.80 | JUN (0.35) | — | |
| SCHEMBL6219443 | 0.75 | ALDH1A1 (0.49) | KMT2AMEN1 | |
| SCHEMBL6223305 | 0.73 | PDE3B (0.34) | — | |
| SCHEMBL4750486 | 0.69 | GRM2 (0.42) | KMT2AMEN1 | |
| SCHEMBL6179642 | 0.68 | CES1 (0.41) | KMT2AMEN1 | |
| SCHEMBL6222347 | 0.67 | KIF11 (0.41) | KMT2A | |
| SCHEMBL4752992 | 0.67 | KIF11 (0.41) | KMT2A | |
| SCHEMBL24355256 | 0.67 | GSK3B (0.44) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551811-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | Amgen Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035549-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | AMGEN INC. (US) | 2004-04-29 | — | — | WO | disclosed |