Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6216306 | 0.99 | THRB (0.40) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL6214060 | 0.75 | L3MBTL1 (0.49) | SMN1; SMN2L3MBTL1MAPTPOLBKMT2A | |
| SCHEMBL4438571 | 0.74 | SMN1; SMN2 (0.52) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL3887651 | 0.74 | SMN1; SMN2 (0.52) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL6213373 | 0.74 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1MAPTPOLBKMT2A | |
| SCHEMBL6217295 | 0.74 | THRB (0.47) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL6213516 | 0.73 | SMN1; SMN2 (0.54) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL6217535 | 0.73 | THRB (0.47) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL11078528 | 0.72 | NPC1 (0.46) | THRBSMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL6221031 | 0.71 | LMNA (0.38) | THRBSMN1; SMN2L3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | disclosed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |