Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218576 | 0.80 | ALDH1A1 (0.43) | KDM4EPOLBALDH1A1HSD17B10HPGD | |
| SCHEMBL6096143 | 0.79 | BRD4 (0.39) | ALDH1A1HPGD | |
| SCHEMBL4774953 | 0.76 | CHRNA7 (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL6245889 | 0.75 | — | — | |
| SCHEMBL7247349 | 0.75 | CYP1A2 (0.42) | POLBALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6097431 | 0.66 | BRD4 (0.39) | GAA | |
| SCHEMBL5117067 | 0.65 | MAPT (0.39) | KDM4EPOLBALDH1A1GAAMAPT | |
| SCHEMBL24879683 | 0.63 | KDM4E (0.44) | KDM4EPOLBALDH1A1GAAMAPT | |
| SCHEMBL3667956 | 0.63 | KMT2A (0.69) | KDM4EPOLBALDH1A1HSD17B10HPGD | |
| SCHEMBL15063359 | 0.63 | MAPT (0.48) | KDM4EPOLBALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511746-A2 | PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES | 3M Innovative Properties Company (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6743920-B2 | CHORINATION REPLACING HYDROXYL GROUPS OF 2,4-DIHYROXY-3-NITROPYRIDINE DERIVATIVE; AMINATION, HYDROXYARYLATION, REDUCTION AND CYCLIZATION; AMINE REPLACEMENT OF PHENOXY FUNCTIONALITY | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-18 | — | — | US | disclosed |
| WO-2003101949-A2 | PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | CPNE4, HTR4, IL4 | KDM4E 136/4885POLB 1426/4885ALDH1A1 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.