Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP1 | O60894 | 3/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5640381 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBMMEACE | |
| SCHEMBL6224010 | 0.79 | HTT (0.39) | RAMP1CALCRLALDH1A1KDM4EPOLB | |
| SCHEMBL5637058 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBMMEACE | |
| SCHEMBL5637053 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBMMEACE | |
| SCHEMBL5637529 | 0.74 | NCF1 (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL6230527 | 0.72 | CALCRL (0.57) | RAMP1CALCRLMMEACE | |
| SCHEMBL92506 | 0.71 | L3MBTL1 (0.63) | ALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL6224332 | 0.71 | CCR2 (0.56) | ALDH1A1 | |
| SCHEMBL6224270 | 0.70 | LMNA (0.42) | RAMP1CALCRL | |
| SCHEMBL9090627 | 0.70 | L3MBTL1 (0.61) | ALDH1A1KDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534681-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004002960-A1 | SUBSTITUTED QUINOLINE CCR5 RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-01-08 | — | — | WO | disclosed |