Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | ESR1 | P03372 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | CA3 | P07451 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4'-Methylenedianiline SCHEMBL10904310 | 0.89 | ALDH1A1 (0.75) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| SCHEMBL36454 | 0.86 | ESR1 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| SCHEMBL2969737 | 0.86 | ESR1 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| SCHEMBL1304762 | 0.86 | CYP3A4 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| SCHEMBL3482770 | 0.86 | CYP3A4 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| SCHEMBL8094139 | 0.86 | CYP3A4 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| 4,4'-Methylenedianiline SCHEMBL15105282 | 0.86 | CYP3A4 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| 4,4'-Methylenedianiline SCHEMBL28001 | 0.86 | CYP3A4 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| SCHEMBL6362775 | 0.86 | CYP3A4 (1.00) | ALDH1A1CYP3A4ESR1TDP1ESR2 | |
| 4,4'-Methylenedianiline SCHEMBL29147413 | 0.85 | ABAT (0.61) | ALDH1A1CYP3A4ESR1TDP1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737398-A | POLYAZOMETHYNE, POLYESTER OR POLYCARBONATE | POLYPLASTICS CO., LTD. (JP) | 1988-04-12 | — | — | US | claimed |
| US-20240191137-A1 | THERMOPLASTIC COMPOSITIONS AND USES THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-06-13 | — | — | US | disclosed |
| WO-2024095883-A1 | MODIFIER FOR THERMOPLASTIC RESIN, RESIN COMPOSITION, AND USE OF ROSIN RESIN | 荒川化学工業株式会社 | 2024-05-10 | — | — | WO | disclosed |
| WO-2024095880-A1 | MODIFYING AGENT FOR THERMOPLASTIC RESINS, RESIN COMPOSITION, AND USE OF HYDROGENATED AROMATIC HYDROCARBON RESIN | 荒川化学工業株式会社 | 2024-05-10 | — | — | WO | disclosed |
| WO-2024095878-A1 | MODIFIER FOR THERMOPLASTIC RESIN, RESIN COMPOSITION, USE OF HYDROGENATED AROMATIC HYDROCARBON RESIN, TACKIFIER, AND PRESSURE-SENSITIVE ADHESIVE OR ADHESIVE COMPOSITION | 荒川化学工業株式会社 | 2024-05-10 | — | — | WO | disclosed |
| US-20230312874-A1 | COMPOUND, RUBBER MIXTURE CONTAINING THE COMPOUND, VEHICLE TIRE WHICH HAS AT LEAST ONE COMPONENT COMPRISING THE RUBBER MIXTURE, METHOD FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGING PROTECTION AGENT AND/OR ANTIOXIDANT AGENT AND/OR ANTIOZONANT AND/OR DYE | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-3143010-B1 | ENERGY EFFICIENT MANUFACTURING PROCESS FOR PREPARING N,O-TRIGLYCIDYL AMINOPHENOLS | ADITYA BIRLA CHEMICALS THAILAND LTD (TH) | 2020-04-08 | — | — | EP | disclosed |
| CN-106536493-B | Energy efficient manufacturing process for the preparation of N, O-triglycidyl aminophenols | 阿迪亚波拉化学品（泰国）有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-109071784-A | Polycarbonate resin fluidity improver and its manufacturing method and poly carbonate resin composition and its molded product | 株式会社钟化 | 2018-12-21 | — | — | CN | disclosed |
| US-10023548-B2 | Energy efficient manufacturing process for preparing N,O-triglycidyl aminophenols | ADITYA BIRLA CHEMICALS (THAILAND) LTD. (TH) | 2018-07-17 | — | — | US | disclosed |
| EP-0063881-A1 | Poly(ester-amide) derived from p-hydroxybenzoic acid, 2,6-naphthalene-dicarboxylic acid and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-11-03 | — | — | EP | disclosed |
| US-4355132-A | Anisotropic melt phase forming poly(ester-amide) derived from p-hydroxybenzoic acid, 2,6-naphthalenedicarboxylic acid, aromatic monomer capable of forming an amide linkage, and, optionally, hydroquinone and additional carbocyclic dicarboxylic acid | CELANESE CORPORATION (US) | 1982-10-19 | — | — | US | disclosed |
| US-4351918-A | Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, other aromatic hydroxyacid, carbocyclic dicarboxylic acid, and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |
| US-4341688-A | Poly(ester-amide) capable of forming an anisotropic melt phase derived from dihydroxyanthraquinone, hydroxybenzoic acid, dicarboxylic acid, and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-07-27 | — | — | US | disclosed |
| US-4339375-A | Poly(ester-amide) capable of forming an anisotropic melt phase derived from p-hydroxybenzoic acid, 2,6-dihydroxynaphthalene, carbocyclic dicarboxylic acid, aromatic monomer capable of forming an amide linkage, and, optionally, additional aromatic diol | CELANESE CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0053940-A1 | Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, dicarboxylic acid and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-06-16 | — | — | EP | disclosed |
| US-4330457-A | Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, dicarboxylic acid, and aromatic monomer capable of forming an amide linkage | CELANESE CORPORATION (US) | 1982-05-18 | — | — | US | disclosed |
| US-4094861-A | Process for the production of non-inflammable polytriazines | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-13 | — | — | US | disclosed |
| US-4059567-A | High molecular weight polytriazines of soluble polymeric N-cyano-isourea ethers | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023548-B2 | Energy efficient manufacturing process for preparing N,O-triglycidyl aminophenols | HPD, PAH, ATIC | ALDH1A1 1024/4885CYP3A4 28/4885ESR1 97/4885 |
| US-20230312874-A1 | COMPOUND, RUBBER MIXTURE CONTAINING THE COMPOUND, VEHICLE TIRE WHICH HAS AT LEAST ONE COMPONENT COMPRISING THE RUBBER MIXTURE, METHOD FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGING PROTECTION AGENT AND/OR ANTIOXIDANT AGENT AND/OR ANTIOZONANT AND/OR DYE | POT1, RIF1, TERT | ALDH1A1 1949/4885CYP3A4 832/4885ESR1 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.