Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.55 |
| ▸ | EIF4E | P06730 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194932 | 0.87 | ABCB1 (0.52) | EIF4EABCB1AKR1C3AKR1C2AKR1B10 | |
| SCHEMBL147187 | 0.84 | AKR1C3 (0.63) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| Hydrochloric Acid SCHEMBL11773334 | 0.83 | AKR1C3 (0.61) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL5193454 | 0.82 | CRHBP (0.59) | ABCB1MAPTTSHR | |
| SCHEMBL8375405 | 0.82 | TDP1 (0.52) | ABCB1MAPTTSHR | |
| SCHEMBL13890931 | 0.82 | ALOX5 (0.43) | FBP1EIF4EABCB1DHODHMAPT | |
| SCHEMBL6225602 | 0.82 | ABCB1 (0.50) | FBP1EIF4EABCB1AKR1C3AKR1C2 | |
| SCHEMBL4405072 | 0.81 | CYP1A2 (0.53) | FBP1EIF4EABCB1NPC1CASP3 | |
| SCHEMBL4414605 | 0.81 | FBP1 (0.49) | FBP1EIF4EABCB1AKR1C3AKR1C2 | |
| SCHEMBL4414607 | 0.81 | FBP1 (0.49) | FBP1EIF4EABCB1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534689-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-06-01 | — | — | EP | disclosed |
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| WO-2004024702-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | FBP1 1388/4885EIF4E 1130/4885ABCB1 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.