Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223731 | 0.82 | CYP19A1 (0.40) | TNFRSF1AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL701444 | 0.81 | GPR35 (0.46) | TNFRSF1AKDM4EMEN1KMT2AATM | |
| SCHEMBL6226642 | 0.69 | CYP19A1 (0.39) | TNFRSF1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9670322 | 0.67 | USP2 (0.47) | KDM4EMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL6221773 | 0.67 | HSD17B10 (0.54) | TNFRSF1AKDM4EMEN1KMT2AATM | |
| SCHEMBL6170913 | 0.66 | KMO (0.48) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL333985 | 0.66 | SLC16A3 (0.40) | TNFRSF1A | |
| SCHEMBL9243077 | 0.64 | CCR2 (0.47) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5797666 | 0.63 | MAPT (0.48) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL5240000 | 0.63 | KDM4E (0.80) | KDM4EMEN1KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068858-B1 | Use of 4,6-dimethoxyindole-2-carboxylic acid for stimulating or inducing hair growth and/or arresting hair loss | OREAL (FR) | 2005-04-13 | — | — | EP | claimed |
| EP-1068865-B1 | Use of 4,6-dimethoxy-indole 2-carboxylic acid or derivatives thereof for seborrhea treatment | OREAL (FR) | 2005-03-16 | — | — | EP | claimed |