Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733102 | 0.84 | KMT2A (0.40) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL8849128 | 0.83 | POLB (0.38) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL4575872 | 0.81 | KDM4E (0.35) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL1720844 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL1152756 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL5747695 | 0.70 | TSHR (0.43) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL9727303 | 0.64 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL9727504 | 0.63 | FKBP1A (0.53) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL8877101 | 0.63 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL16554340 | 0.63 | ALDH1A1 (0.37) | ALDH1A1KDM4ETSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606254-A1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080962-A1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |