Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849128 | 0.90 | POLB (0.38) | KDM4EALDH1A1TSHRFKBP1AMAPK1 | |
| SCHEMBL1720844 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1TSHRFKBP1AMAPK1 | |
| SCHEMBL6228181 | 0.81 | ALDH1A1 (0.43) | KDM4EALDH1A1TSHRMAPK1KMT2A | |
| SCHEMBL5733102 | 0.76 | KMT2A (0.40) | KDM4EALDH1A1TSHRMAPK1RECQL | |
| SCHEMBL5747695 | 0.74 | TSHR (0.43) | KDM4EALDH1A1TSHRMAPK1RECQL | |
| SCHEMBL2430037 | 0.72 | KMT2A (0.35) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2431064 | 0.71 | MAPT (0.35) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9727504 | 0.69 | FKBP1A (0.53) | KDM4EALDH1A1TSHRFKBP1AMAPK1 | |
| SCHEMBL8877101 | 0.68 | ALDH1A1 (0.42) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL9727245 | 0.68 | FKBP1A (0.51) | KDM4EALDH1A1TSHRFKBP1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989162-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007096058-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-08-30 | — | — | WO | disclosed |