Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849128 | 0.85 | POLB (0.38) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPK1 | |
| SCHEMBL4575872 | 0.82 | KDM4E (0.35) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPK1 | |
| SCHEMBL6228181 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPK1 | |
| SCHEMBL1722174 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2TSHRTP53 | |
| SCHEMBL3761042 | 0.73 | LMNA (0.40) | ALDH1A1KDM4ESMN1; SMN2TSHRTP53 | |
| SCHEMBL5733102 | 0.72 | KMT2A (0.40) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPK1 | |
| SCHEMBL5747695 | 0.69 | TSHR (0.43) | ALDH1A1KDM4ESMN1; SMN2TSHRMAPT | |
| SCHEMBL3763744 | 0.67 | AGBL2 (0.45) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL3765143 | 0.67 | MEN1 (0.41) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL13191751 | 0.66 | MAPT (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406216-A2 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | Bayer Cropscience AG (DE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010102758-A2 | HALOGENALKYLMETHYLENOXY-PHENYL-SUBSTITUTED KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | WO | disclosed |